Phenoxypropylamine derivatives

Details Phenoxypropylamine derivatives Phenoxypropylamine derivatives

1974-12-17

1976-09-28

Curtis, Allen B.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602475R, 26029379, 2603265J, 2603265L, 26032685, 260559A, 2605707, 260553A, 260465E, C07C 8752, C07C11100

Patent

active

039831698

ABSTRACT:
Phenoxypropylamine derivatives of the general formula: ##EQU1## in which R is a hydrogen atom or a straight-chain or branched alkyl group containing up to 10 carbon atoms, R.sub.1 is a hydrogen atom, a straight-chain or branched alkyl group containing up to 10 carbon atoms or a cyclopentyl, cyclohexyl, benzyl or phenyl group or R and R.sub.1 taken together form a pentamethylene-(1,5), tetramethylene-(1,4), 2-azapentamethylene-(1,5), 3-azapentamethylene-(1,5) or 3-oxapentamethylene-(1,5)-group, R.sub.2 is a hydrogen atom or an alkyl group containing up to 6 carbon atoms or a benzyl or phenyl group, R.sub.3 is a branched alkyl group containing 3 to 6 carbon atoms, a cyanoalkyl group containing up to 6 carbon atoms or a cycloalkyl group containing 3 to 7 carbon atoms and R.sub.4 is a hydrogen atom, an alkyl group containing up to 6 carbon atoms or a benzyl group, and the pharmaceutically-acceptable salts thereof having a cardioselective .beta.-blocking action.

REFERENCES:
patent: 3852339 (1974-12-01), Krapcho

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