Phenoxypropoxy halophenylacetic acids as leukotriene antagonists

Details Phenoxypropoxy halophenylacetic acids as leukotriene antagonists Phenoxypropoxy halophenylacetic acids as leukotriene antagonists

1986-04-22

1989-04-11

Sutto, Anton H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

548134, 548353, 564 99, 568325, C07C 6501

Patent

active

048208671

ABSTRACT:
Compounds of the formula: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic and anti-inflammatory agents.

REFERENCES:
patent: 3899513 (1975-08-01), Warren et al.
Bailey et al., Ann. Rpts., Med. Chem., 17, 203 (1982).

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