Phenoxypropanolamine therapeutic agents

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 31165

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active

039610721

ABSTRACT:
A series of novel substituted phenoxypropylamine derivatives have been prepared by reacting the appropriate 1-phenoxy-2,3-epoxypropane compound with a suitable organic amine reagent. The resulting 1-phenoxy-3-alkylaminopropan-2-ols are useful in the field of chemotherapy as anti-angina agents. Preferred members include compounds having an acetamido group substituted on the phenyl ring of the phenoxy moiety. Alternate methods of preparation are also provided.

REFERENCES:
patent: 3337628 (1967-08-01), Smith et al.
patent: 3562297 (1971-02-01), Howe et al.
patent: 3574749 (1971-04-01), Howe et al.

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