Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1996-10-18
1997-09-16
Gupta, Yogendra N.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
5142312, 514255, 514256, 514428, 514452, 544146, 544153, 544242, 544336, 549220, 549362, 549434, 549469, 562446, 562447, 562466, 562467, A61K 3119, A61K 31535, C07D26530, C07C 5911
Patent
active
056681763
ABSTRACT:
Phenoxyphenylacetic acids and derivatives of the general structural formula I ##STR1## have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.
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Bagley Scott W.
Broten Theodore P.
Chakravarty Prasun K.
Dhanoa Daljit S.
Fitch Kenneth J.
Camara Valerie J.
Daniel Mark R.
Gupta Yogendra N.
Merck & Co. , Inc.
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