Phenoxyalicyclic carboxylic acid derivatives

Details Phenoxyalicyclic carboxylic acid derivatives Phenoxyalicyclic carboxylic acid derivatives

1973-05-30

1978-04-04

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

260520B, 424308, 424317, C07C 6976

Patent

active

040829138

ABSTRACT:
Novel anti-atherosclerosis agents having the formula, ##STR1## wherein R is hydrogen or lower alkyl, n and m each signify an integer of 4 - 6, and A is hydrogen or a group of the formula, ##STR2## WHEREIN R and m have the same meanings as defined above. These compounds are produced, for example, by reacting a bisphenolic compound of the formula, ##STR3## with chloroform and a ketone compound of the formula, ##STR4## in the presence of an alkali. Alternatively, they are produced by reacting the bisphenolic compound with .alpha.-halogeno- or .alpha.-hydroxycarboxylic acid derivative of the formula, ##STR5## wherein R and m have the same meanings as defined above, and X is halogen or hydroxyl.

REFERENCES:
patent: 2370256 (1945-02-01), Niederl
patent: 3097139 (1963-07-01), Thorp
patent: 3262850 (1966-07-01), Jones et al.
patent: 3332957 (1967-07-01), Bencze
patent: 3546273 (1970-12-01), Bolhofer
patent: 3716583 (1973-02-01), Nakamura et al.
patent: 4008265 (1977-02-01), Suzuki et al.

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