Phenoxy carboxylic acid derivative

Details Phenoxy carboxylic acid derivative Phenoxy carboxylic acid derivative

1972-09-25

1977-06-21

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260473G, C07C 6514, C07C 6976

Patent

active

040311341

ABSTRACT:
Novel anti-atherosolerosis agents having the formula, ##STR1## wherein typical examples of R.sup.1 and R.sup.2 are hydrogen, C.sub.1 -C.sub.8 alkyl, phenyl, benzyl and phenethyl, or R.sup.1 and R.sup.2 may form cycloalkylidene together with a carbon atom bonded therewith; R.sup.3 and R.sup.4 each is hydrogen or C.sub.1 -C.sub.4 alkyl; Y is hydroxyl, C.sub.1 -C.sub.4 alkoxy, phenoxy or an amine residue; A is hydrogen or a group of the formula, ##STR2## wherein R.sup.3, and R.sup.4 and Y have the same meanings as defined above; and D and E each is hydrogen or halogen.
These compounds are produced, for example, by reacting a bisphenolic compound of the formula, ##STR3## with chloroform and a ketone compound of the formula,

REFERENCES:
patent: 2370256 (1945-02-01), Niederl
patent: 2444594 (1948-07-01), Day et al.
patent: 2482706 (1949-09-01), Day
patent: 2541003 (1951-02-01), Day et al.
patent: 3097139 (1963-07-01), Thorp
patent: 3169144 (1965-02-01), Cavallini et al.
patent: 3262850 (1966-07-01), Jones et al.
patent: 3470235 (1969-09-01), Jackson et al.
patent: 3630715 (1971-12-01), Guttag
Bourley "Medicinal Chemistry" 3rd Ed. (1970) pp. 25-28.

Affiliated with

Also associated with

Rating

Phenoxy carboxylic acid derivative does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phenoxy carboxylic acid derivative, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenoxy carboxylic acid derivative will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-735971