Phenoxy-amino-propanols

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Bacterium or component thereof or substance produced by said...

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Details

2603405R, 424330, A61K 3136, A61K 31135, C07D31706

Patent

active

041713702

ABSTRACT:
New phenoxy-amino-propanols of formula ##STR1## wherein R.sup.1 is alkenyl, alkynyl, alkoxyalkyl or alkenyloxyalkyl with 2-6 C atoms in each case or cycloalkyl with 3-8 C atoms; and R.sup.2 is alkyl or hydroxyalkyl with 1-6 C atoms in each case, cycloalkyl with 3-8 C atoms, aralkyl or aralkyl wherein the aryl radical is mono- to tri-substituted by alkyl, alkoxy, OH, F and/or Cl or mono-substituted by methylenedioxy, with a total of 7-15 C atoms in each case, and the physiologically acceptable acid addition salts thereof, exhibit various pharmacological properties including isoprenaline-antagonism on the heart rate and blood pressure.

REFERENCES:
patent: 3644469 (1972-02-01), Koppe et al.
patent: 3732253 (1973-05-01), Cavalleri et al.
patent: 3966770 (1976-06-01), Kaiser et al.
patent: 4067904 (1978-01-01), Comer et al.

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