Phenoxiacetic acid derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ether doai

Reexamination Certificate

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Reexamination Certificate

active

08003703

ABSTRACT:
The invention relates to certain 2-substituted phenoxyacetic acid derivatives of formula (I), in which the variables are as defined in the claims, useful in the treatment of diseases or conditions in which modulation of the CRTh2 receptor is beneficial, such as asthma and rhinitis.

REFERENCES:
patent: 3278524 (1966-10-01), Johnson et al.
patent: 3920846 (1975-11-01), Hanauye et al.
patent: 3985779 (1976-10-01), Tanaka et al.
patent: 4234742 (1980-11-01), Cognacq et al.
patent: 4248618 (1981-02-01), Serban et al.
patent: 4670566 (1987-06-01), Walsh et al.
patent: 5006542 (1991-04-01), Hall et al.
patent: 5145790 (1992-09-01), Mattingly et al.
patent: 5411972 (1995-05-01), Komoto et al.
patent: 5413891 (1995-05-01), Matsuura et al.
patent: 5532371 (1996-07-01), Komoto et al.
patent: 5703099 (1997-12-01), Hamanaka et al.
patent: 6150413 (2000-11-01), Bernardon et al.
patent: 6376546 (2002-04-01), Shoda et al.
patent: 6417212 (2002-07-01), Brooks et al.
patent: 7056942 (2006-06-01), Hildesheim et al.
patent: 7067507 (2006-06-01), Pullet et al.
patent: 7737135 (2010-06-01), Luker et al.
patent: 2004/0029933 (2004-02-01), Zhao et al.
patent: 2004/0097555 (2004-05-01), Ohkawa et al.
patent: 2004/0220237 (2004-11-01), Fu et al.
patent: 2005/0239881 (2005-10-01), Dunn et al.
patent: 2006/0211765 (2006-09-01), Pairaudeau et al.
patent: 2006/0264435 (2006-11-01), Bonnert et al.
patent: 2006/0293352 (2006-12-01), Bonnert et al.
patent: 2007/0249686 (2007-10-01), Bonnert et al.
patent: 2008/0114002 (2008-05-01), Bonnert et al.
patent: 2008/0132480 (2008-06-01), Luker et al.
patent: 2008/0255150 (2008-10-01), Luker
patent: 2008/0293775 (2008-11-01), Bonnert et al.
patent: 2009/0012151 (2009-01-01), Bonnert et al.
patent: 2009/0036535 (2009-02-01), Luker et al.
patent: 2009/0149448 (2009-06-01), Alcaraz et al.
patent: 2009/0192163 (2009-07-01), Luker et al.
patent: 2010/0160285 (2010-06-01), Luker et al.
patent: 432119 (1967-09-01), None
patent: A-2832435 (1979-02-01), None
patent: 0006789 (1980-01-01), None
patent: 0114734 (1984-08-01), None
patent: 0455058 (1991-11-01), None
patent: 0540165 (1993-05-01), None
patent: 0622690 (1994-11-01), None
patent: 0622816 (1994-11-01), None
patent: 0839808 (1998-05-01), None
patent: 1012142 (2000-06-01), None
patent: 1170594 (2002-01-01), None
patent: 1211513 (2002-06-01), None
patent: 1471057 (2004-10-01), None
patent: 690816 (1953-04-01), None
patent: 1 356 834 (1974-06-01), None
patent: 1 464 977 (1977-02-01), None
patent: 1 469 687 (1977-04-01), None
patent: 2 031 408 (1980-04-01), None
patent: 2 041 363 (1980-09-01), None
patent: 1 585 963 (1981-03-01), None
patent: 07140725 (1995-06-01), None
patent: 2003-508389 (2003-03-01), None
patent: 2006-521382 (2006-09-01), None
patent: 2006-522117 (2006-09-01), None
patent: WO 93/12086 (1993-06-01), None
patent: WO 97/08126 (1997-03-01), None
patent: WO 98/03164 (1998-01-01), None
patent: WO 99/11605 (1999-03-01), None
patent: WO 99/11627 (1999-03-01), None
patent: WO 01/16120 (2001-03-01), None
patent: WO 01/60807 (2001-08-01), None
patent: WO 01/81312 (2001-11-01), None
patent: WO 01/92224 (2001-12-01), None
patent: WO 03/064387 (2003-08-01), None
patent: WO 03/066047 (2003-08-01), None
patent: WO 03/068744 (2003-08-01), None
patent: WO 03/097042 (2003-11-01), None
patent: WO 03/097598 (2003-11-01), None
patent: WO 03/101961 (2003-12-01), None
patent: WO 2004/007451 (2004-01-01), None
patent: WO 2004/048314 (2004-06-01), None
patent: WO 2004/058164 (2004-07-01), None
patent: WO 2004/089884 (2004-10-01), None
patent: WO 2004/089885 (2004-10-01), None
patent: WO 2004/094386 (2004-11-01), None
patent: WO 2004/096777 (2004-11-01), None
patent: WO 2005/018529 (2005-03-01), None
patent: WO 2005/044260 (2005-05-01), None
patent: WO 2005/105727 (2005-11-01), None
patent: WO 2005/115382 (2005-12-01), None
patent: WO 2006/005909 (2006-01-01), None
patent: WO 2006/021759 (2006-03-01), None
patent: WO 2006/037982 (2006-04-01), None
patent: WO 2006/056752 (2006-06-01), None
patent: WO 2006/125596 (2006-11-01), None
patent: WO 2007/039736 (2007-04-01), None
patent: WO 2007/039741 (2007-04-01), None
patent: WO 2007/052023 (2007-05-01), None
patent: WO 2007/068894 (2007-06-01), None
Hazeldine, et al. Design, Synthesis and Biological Evaluation of Analogues of the Antitumor Agent, 2-{4-[(7-Chloro-2-quinoxalinyl)oxy]phenoxy}propionic Acid (XK469). J. Med. Chem. 2001, 44, 1758-1776.
Cecil Textbook of Medicine, 20th edition (1996), vol. 2, pp. 2050-2057.
Cecil Textbook of Medicine, 20th edition (1996), vol. 2, pp. 1992-1996.
FDA mulls drug to slow late-stage Alzheimer's [online], [retrieved on Sep. 23, 2003]. Retrieved from the Internet, URL; http://www.cnn.com/2003/HEALTH/condtions/09/24/alzheimers.drug.ap/indexhtml>.
Lupus erythematosus [online], [retrieved on Dec. 28, 2006]. Retrieved from the Internet, URL; http://en.wikipedia.org/wiki/Lupus—erythematosus>.
Advanced Drug Delivery Reviews 48 (2001) 3-26.
Inflammatory Bowel Disease [online] {retrieved on Apr. 7, 2008 from the Internet} {URL:http://www.emedicinehealth.com/script/main/art.asp?articlekey=59121&pf=3&page=8}.
Rheumatoid arthritis [online] {retrieved on Apr. 7, 2008 from the Internet} {URL:http://www.nlm.nih.gov/medlineplus/ency/article/000431.htm}.
RN 110624-55-0, retrieved from CAPLUS; retrieved on Apr. 7, 2008.
Amin et al., “The Fries Reaction: Part VI—the rearrangement of aryl p-toluene-sulphonates & a convenient method for synthesis of hydroxy-diarylsulphones”,Journal of Scientific Industrial Research, vol. 13B, 1954, pp. 181-183.
Atkinson et al., “Substituted (2-Phenoxyphenyl)acetic Acids with Antiinflammatory Activity”,J. Med. Chem., vol. 26, 1983, pp. 1353-1360.
Baliah et al., “Fries rearrangement of the benzenesulphonates of xylenols”,Recueil des Travaux Chimiques des Pays-Bas, vol. 80, 1961, pp. 139-148.
Bartl et al., “Thioxanthene Derivatives of Pharmacological Interest: 1,2,4-Trichloro and 2,4,5,6-Tetrachloro Derivatives of 9-(3-Dimethylaminopropylidene)Thioxanthene”,Collection Czechoslov. Chem. Commun., vol. 49, 1984, pp. 2295-2308.
Brown et al., “Some Chlorinated Hydroxyphenoxyacetic Acids”,Journal of the Chemical Society, 1955, pp. 3681-3687.
Budavari, S., “The merck Index, 13thedition”, p. 3106, monograph 3108, XP-002347170, 2001.
Cavill et al., “The chemistry of plant-growth regulators. Part I. 2:4-dichloro-6-hydroxyphenoxyacetic acid and related compounds”,Journal of the Chemical Society, 1954, pp. 565-569.
Clemo et al., “Strychnine and brucine. Part II”,Journal of the Chemical Society,vol. 125, 1924, pp. 1751-1804, XP008053173.
Cocco et al., “Annulation of functionalized hexadienones as an efficient regioselective approach to N-Aryl-2-(trifluoromethyl)-4-pyridinamines”,Tetrahedron Letters, vol. 40, No. 23, 1999, pp. 4407-4410.
Gallo et al., “Spirodioxolanonarenones. II. Synthesis of a halogenated 1,4-dioxaspiro[4,5] deca-7,9-diene-2,6-dione”,Journal of Chemistry, vol. 30, No. 5, 1965, pp. 1657-1658.
Gaunt et al., “Metabolism of 4-chloro-2-methylphenoxyacetate by a soil pseudomonad”,Biochem. J., vol. 122, 1971, pp. 519-526.
Huston et al., “Chloro derivatives ofo- andp-benzyl phenols. II. Some monochloro, dichloro and trichloro derivatives of ortho and para benzyl phenols”,Journal of the American Chemical Society, vol. 55, No. 11, 1933, pp. 4639-4643.
Inukai et al., “ortho-DisubstitutedF-benzenes. III. Preparation of (F-benzo)heterocyclic compounds fromF-benzoic acid andF-phenol, and the reactions of some intermediaryF-benzoyl- and F-phenoxy compounds”,Bull. Chem. Soc. Jpn., vol. 54, No. 11, 1981, pp. 3447-3452.
Janczewski et al., “Effect of Molecular Structure on Optical Properties of Sulfoxide Systems.o-Phenoxyphenylsulfinylacetic Acid and some of Their Derivatives. Part II”,Polish Journal of Chemistry, vol. 62, No. 1-3, 1964, pp. 91-105, XP008053171.
Kmonicek et al., “(Tert-Amino)-11-(4-Methylpiperazin

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