Phenothiazine derivatives, their production and use

Details Phenothiazine derivatives, their production and use Phenothiazine derivatives, their production and use

1992-04-14

1994-09-06

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D27928

Patent

active

053449282

ABSTRACT:
There is disclosed a novel phenothiazine derivative of the general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and are a C.sub.1-6 alkyl group and at least one of them has as a substituent a group which can react with amino group, thiol group or carboxyl group, and X.sup.- is a counter ion of the phenazathionium. Their production and the intermediates used in the production are also disclosed. The compound (I) is a derivative of methylene blue and is applicable to photodynamic therapy of cancer or immunoassays utilizing chemiluminescence.

REFERENCES:
patent: 3873340 (1975-03-01), Miyazawa et al.
patent: 4394443 (1983-07-01), Weissman et al.
patent: 4548904 (1985-10-01), Kent et al.
patent: 4652643 (1987-03-01), Gunn et al.
patent: 4714763 (1987-12-01), Theodoropulos
patent: 4962197 (1990-10-01), Foley et al.
Inoue et al., "Cloning and Sequencing of the Gene Encoding . . . " J. of Bacteriology 171: 3115-3122 (Jun. 1989).
Nunn et al., "Isolation and Complementation of 10 Methanol . . . " J. of Bacteriology 166: 581-597 (May 1986).

Affiliated with

Also associated with

Rating

Phenothiazine derivatives, their production and use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Phenothiazine derivatives, their production and use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Phenothiazine derivatives, their production and use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1330279