Phenothiazine derivatives and a process for their preparation

Details Phenothiazine derivatives and a process for their preparation Phenothiazine derivatives and a process for their preparation

1980-05-02

1981-09-15

Randolph, John D.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544 39, A61K 31415, C07D27930

Patent

active

042897688

ABSTRACT:
Phenothiazine derivatives of the formula ##STR1## wherein R is H, F, Cl, Br, I, CH.sub.3, CF.sub.3, CN, CH.sub.3 O or CH.sub.3 CO; Y is S, SO, or SO.sub.2 ; Z is imidazol-1-yl, 2-methyl-imidazol-1-yl, pyrazol-1-yl or benzimidazol-1-yl; and n is 1, 2 or 3; or the physiologically acceptable acid addition salts thereof; are useful as antihypertensive agents, for example.

REFERENCES:
patent: 2591679 (1952-04-01), Cusic
Schenker-Herbst, Arzeimittel-Forschung (Drug Research), vol. 5, edited by Ernst Jucker, pp. 484 to 497, Birkhauser Verlag Basel und Stuttgart, Printed in Switzerland (1963).

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