Phenolic thioethers as inhibitors of 5-lipoxygenase

Details Phenolic thioethers as inhibitors of 5-lipoxygenase Phenolic thioethers as inhibitors of 5-lipoxygenase

1988-05-23

1989-07-11

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Sulfur, selenium or tellurium compound

514708, 514731, A61K 3110, A61K 31095, A61K 3105

Patent

active

048473057

ABSTRACT:
The compounds of the present invention comprise substituted phenolic thioether derivatives that are specific inhibitors of 5-lipoxygenase and which, therefore, are useful in the treatment of local and systemic inflammation, allergy and hypersensitivity reactions and other disorders in which agents formed in the 5-lipoxygenase metabolic pathway are involved.

REFERENCES:
patent: 3886285 (1975-05-01), Bentley et al.
Chem. Abst. 89-(1978)-27167 J+94 (1981)-30290c.
Chem. Abstracts 83: 27876r (1975).
Chem. Abstracts 73: 45047u (1970).

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