Phenolic amine depigmenting and antimelanoma agents

Drug – bio-affecting and body treating compositions – Bleach for live hair or skin

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424423, 424 59, 514649, A61K 7135, A61K 31135, A61F 202

Patent

active

053956117

ABSTRACT:
A composition useful for treating skin pigmentation, melasma and melanoma comprises:

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J. Pankovich et al., 4-S-Cysteaminylphenol and its Analogues as Substrates for Tyrosinase and Monoamine Oxidase, Munksgaard, Pigment Cell Research, 3:146-149(1990).
Miura et al., "Synthesis of Cysteinylphenol, Cysteaminylphenol, and Related Compounds, and In Vivo Evaluation of Antimelanoma Effect", Arch. Dermatol. Res. (1987) 279:219-225.
Ito et al., "Depigmentation of Black Guinea Pig Skin by Topical Application of Cysteaminylphenol, Cysteinylphenol, and Related Compounds", The Journal of Investigative Dermatology, vol. 88, No. 1, Jan. 1987.
Icke, R. N. et al., "Preparation of B-phenylethyldimethylamine", Org. Syn. Coll. 3:723-725, 1955.
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