Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1987-11-04
1989-04-11
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
564336, 564338, 564339, 564304, A61K 31135
Patent
active
048207349
ABSTRACT:
The novel phenethylamine derivatives of the general formula ##STR1## wherein R.sup.1 and R.sup.2 each signify hydrogen, halogen, trifluoromethyl, lower alkoxy, lower alkyl, hydroxy or nitro, with the proviso that at least one of R.sup.1 and R.sup.2 is different from hydrogen, R.sup.3 and R.sup.4 each signify lower alkyl, n signifies the number 1, 2, 3 or 4 and B signifies the group --CO-- or --CHOH--, and their pharmaceutically acceptable acid addition salts have interesting analgesic and antidepressant properties. These substances can be manufactured according to various methods which are known per se and can be used as medicaments in the form of pharmaceutical preparation.
REFERENCES:
patent: 4017637 (1977-04-01), Yardley et al.
patent: 4535189 (1985-08-01), Husbands et al.
Bernauer Karl
Bruderer Hans
Hoffmann-La Roche Inc.
Leon Bernard S.
Mazza Richard J.
Owens A. A.
Raymond Richard L.
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