Phenethylamine antigenic conjugates, their preparation, antibodi

Details Phenethylamine antigenic conjugates, their preparation, antibodi Phenethylamine antigenic conjugates, their preparation, antibodi

1974-12-10

1976-12-07

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Attached to antibody or antibody fragment or immunoglobulin;...

260112R, 424 7, 424 12, 424 88, G01N 3300, A61K 3900, G21H 502

Patent

active

039963446

ABSTRACT:
Antigenic phenethylamine conjugates are produced by blocking the amine of the phenethylamine hapten with a group, coupling of the phenethylamine to a carrier, and removal of the blocking group. Specific phenethylamines useful in this invention are amphetamine, epinephrine, and norepinephrine. The antigens thus produced can be used to raise antibodies in animal bodies, the antibodies being specific to the phenethylamine compound employed. The antibodies are useful in assaying for the phenethylamine hapten compounds.

REFERENCES:
patent: 3709868 (1973-01-01), Spector
patent: 3856469 (1974-12-01), Schneider et al.
patent: 3878187 (1975-04-01), Schneider et al.
patent: 3884898 (1975-05-01), Schneider
patent: 3901654 (1975-08-01), Gross

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