Phencyclidine derivatives and protein and polypeptide phencyclid

Details Phencyclidine derivatives and protein and polypeptide phencyclid Phencyclidine derivatives and protein and polypeptide phencyclid

1992-04-06

1994-07-19

Kim, Kay K.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Chemical modification or the reaction product thereof, e.g.,...

530405, 530406, 530408, 435188, 435964, 436543, 436544, 546213, C07K 1702, A61K 39385, C07C33308, C07D21100

Patent

active

053311094

ABSTRACT:
The present invention is directed to novel PCP derivatives which are synthesized for the covalent attachment to antigens or receptors (proteins or polypeptides) for the preparation of antibodies or receptors to PCP and PCP analogue metabolites. The resulting novel antigens may be used for the production of antibodies or receptors using standard methods. Once generated, the antibodies and the novel derivatives which are covalently attached to proteins, polypeptides or labels may be used in the immunoassay process.

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Jung et al (1981) Biochem. Biophys. Res. Commun. 101(2):599-606.
Rowley et al (1975) J. Biol. Chem. 250(10):3759-3766.

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