Phenanthridines and phenanthridinones as antiviral agents

Details Phenanthridines and phenanthridinones as antiviral agents Phenanthridines and phenanthridinones as antiviral agents

1974-06-07

1976-01-13

Rosen, Sam

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3147

Patent

active

039326438

ABSTRACT:
Phenanthridines and phenanthridinones of the formulae ##SPC1##
And the pharmaceutically-acceptable acid addition salts thereof wherein X is chloro, bromo, hydroxy, alkoxy having from 1 to 6 carbon atoms, amino, monoalkylamino, dialkylamino wherein each of the alkyl groups has from 1 to 6 carbon atoms, and benzylamino; R is hydrogen, alkyl having from 1 to 6 carbon atoms, --A--NR.sub.1 R.sub.2 wherein each of R.sub.1 and R.sub.2 is alkyl having from 1 to 6 carbon atoms and A is a divalent alkylene radical having from 2 to 6 carbon atoms; and each of Y and Z is hydrogen, and .omega.-dialkylaminoalkoxy wherein the alkyl and alkoxy groups have from 1 to 6 carbon atoms, and from 2 to 6 carbon atoms, respectively; with the proviso that when R is hydrogen or alkyl, each of Y and Z is dialkylaminoalkoxy; useful as antiviral agents and/or interferon inducers and methods for their preparation.

REFERENCES:
patent: 3573312 (1971-04-01), Krimmel
patent: 3641032 (1972-02-01), Rockaway et al.

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