Phenanthrene methanol compounds useful as antimalarial agents

Details Phenanthrene methanol compounds useful as antimalarial agents Phenanthrene methanol compounds useful as antimalarial agents

1992-05-28

1993-10-05

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C07C21516

Patent

active

052507343

ABSTRACT:
A compound represented by the following formula (I): ##STR1## wherein R is hydrogen, methyl, ethyl, propyl, butyl, phenyl, CH.sub.2 CH(OH)CH.sub.3, CH.sub.2 CH(OH)CH(OH), CH.sub.2 CH.sub.2 CH.sub.2 -phenyl, or a group of the formula (CH.sub.2).sub.x -Ar, where x is 0 to 4 and Ar is a 6-membered ring from phenyl, pyridyl, cyclohexyl, or pyranyl, each of which may be substituted with a hydrophilic group(s), and

REFERENCES:
patent: 4178376 (1979-12-01), Higuchi et al.
patent: 4507288 (1985-03-01), Rossignol
patent: 4818767 (1989-04-01), Rossignol
Merck Index, 1989 (Merck & Co., Inc.) p. 4504.

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