Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2006-03-07
2006-03-07
Ungar, Susan (Department: 1642)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S070100, C530S387100, C530S350000, C424S184100, C424S185100, C536S023100
Reexamination Certificate
active
07008779
ABSTRACT:
Described is a novel gene and its encoded basic Helix Loop Helix protein, termed PHELIX, and to diagnostic and therapeutic methods and compositions useful in the management of various cancers which express PHELIX, particularly including prostate cancer, bladder cancer, ovarian cancer and testicular cancer. In human normal tissues, PHELIX is only expressed in testis tissue. However, PHELIX is expressed at high levels in prostate cancer cells and in other cancer cells. The structure of PHELIX suggests that it may function as a transcription factor that normally exhibits a testis-specific expression pattern but is turned on in prostate cancer as well as in other cancers.
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Afar Daniel E.
Hubert Rene S.
Raitano Arthur B.
Agensys, Inc.
Davis Minh Tam
Morrison & Foerster / LLP
Ungar Susan
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