Phase transfer process for producing native plasma protein conce

Details Phase transfer process for producing native plasma protein conce Phase transfer process for producing native plasma protein conce

1993-04-08

1995-05-30

Russel, Jeffrey E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

530380, 530382, 530427, 530830, A61K 3836, C07K 130, C07K 14745, C07K 1475

Patent

active

054202507

ABSTRACT:
Cryoprecipitated mammalian plasma proteins with associated glycoproteins, polysaccharides, and numerous other macromolecular entities are transferred directly in the course of controlled thawing and centrifuging from native plasma phase across the boundary layer into a pre-prepared substrate transfer medium at sustained solidus--liquidus equilibrium regulated to residual icing from about 5 weight percent to about 95 weight percent to produce cryoprecipitates with enhanced productivity and enhanced qualifications for in vivo tissue bonding applications.

REFERENCES:
patent: 2492458 (1944-12-01), Bering et al.
patent: 3297532 (1967-01-01), Jones
patent: 3523870 (1970-08-01), Gerendas et al.
patent: 4216205 (1980-08-01), Radowitz
patent: 4278592 (1981-07-01), Seufert et al.
patent: 4289691 (1981-09-01), Rock et al.
patent: 4298598 (1981-11-01), Schwarz
patent: 4359049 (1982-11-01), Redl et al.
patent: 4362567 (1982-12-01), Schwarz et al.
patent: 4377572 (1983-03-01), Linnau
patent: 4414976 (1983-11-01), Linnau
patent: 4427650 (1984-01-01), Stroetmann
patent: 4600574 (1986-07-01), Lindner
patent: 4608254 (1986-08-01), Philapitsch
patent: 4627879 (1986-12-01), Dresdale et al.
patent: 4631055 (1986-12-01), Habison
patent: 4638048 (1987-01-01), Foster
patent: 4650678 (1987-03-01), Fuhge et al.
patent: 4735616 (1988-04-01), Eible
patent: 4909251 (1990-03-01), Seelich
patent: 4928603 (1990-05-01), Dresdale et al.
patent: 4960757 (1990-10-01), Kumpe et al.
patent: 5321126 (1994-06-01), van Dommelen et al.
Anonymous, Freezing and Thawing Serum Cells, Technical Bulletin, Art to Science, vol. 5, No. 2, HyClone Laboratories, Logan, Utah. 1986.
ASTM Designation D-413--82 Standard Test Methods for Rubber Property--to Flexible Substrate, pp. 70, 71, 73 and 74, 1990.
ASTM Designation F-639-79:85 Standard Specification for Polyethylene Plastics for Medical Applications, p. 164. 1990.
ASTM Designation D-638--68 Standard Method of Test for Tensile Properties of Plastics, p. 189, 195-197, 1990.
Brands et al., Preservation of the Ruptured Spleen by Gluing with Concentrated Fibrinogen. Experimental and Clinical Results. World J. Surg., vol. 6, pp. 366-368, 1982.
Brodniewicz-Proba et al., Modified Glycine Precipitation Technique for the Preparation of Factor VIII Concentrate of High Purity and High Stability Vox-Sang 52:10-14 (1987).
Castillo et al. Prothrombin Times and Clottable Fibrinogen Determination on An Automated Coagulation Laboratrory. Thrombosis Res., pp. 213, 215, 217, 219, 1989.
Cohn et al., J. Am. Chem. Soc., vol. 68, pp. 459-475, 1946.
Conte et al., Infection-Control Guidelines For Patients with the Acquired Immunodeficiency Syndrome (AIDS), The New Eng. Jour. of Med, Sep. 1983, 740-744.
Dresdale et al., Hemostatic Effectiveness of Fibrin Glue Derived from Single-Donor Fresh Frozen Plasma. Ann. Thor. Surg., vol. 40, p. 385-387, 1985.
Dresdale et al., Preparation of Fibrin Glue from Single-Donor Fresh-frozen Plasma, Surgery, vol. 97, pp. 750-754, 1985.
Edsall et al., J. Biol. Chem., vol. 191, pp. 735-756, 1951.
Epstein, et al., Current Safety of Clotting Factor Concentrates Arch. Pathol. Lab. Med. vol. 114; 335-340 1990.
Epstein, G. H. et al., A New Autologous Fibrinogen-Based Adhesive for Otologic Surgery. Ann. Otol. Rhinol Laryngol, vol. 95, pp. 40-45, 1986.
Farrugia et al., "Studies on the procurement of blood coagulation factor VIII . . . ", J. Clin. Pathol. vol. 38, pp. 433-437, 1985.
FDA Drug Bulletin vol. 8, No. 2, pp. 15-16, Mar. Apr. 1978.
Gestring, Gidon F., Autologous Fibrinogen for Tissue-Adhesion, Hemostasis and Embolization pp. 294-296, and 303, 1982.
Grey, R. G. Fibrin as a Hemostatic in Cerebral Surgery. Surg. Gynecol. Obstr. vol. 21, 452-454, 1915.
Hammerstein, O. Arch. Gesamte Physiol, Menschen Tier, vol. 19, pp. 563-622, 1879.
Holmes et al., a-Proteins in Human Cell Cult., In Vitro, vol. 15, pp. 522-530, 1979.
Klein, J., The Interdiffusion of Polymers, Science, vol. 250, pp. 640-641, 1990.
Kram, H. B., et al., "Fibrin Glue Sealing of Polyetetrafluoroethylene Vascular Graft Anastomoses. Comparison with oxidized Cellulose", J. Vascular Surgery, 1988, 8:563-568.
Matras et al., Zur Nachlosen Interfaszikularen Nerventransplantation in Tierexperiment. Wien. Med/Wochenschr. vol. 122, pp. 517-521, 1972.
Putnam, Frank W., Ed. The Plasma Proteins, Ch 2. vol 1, Pennell, Robert B. Fractionation and Isolation and Purified Components by Precipitation Methods, p. 9-50 1960.
Putnam, F. W., Ed. The Plasma Proteins, 2nd Ed., Section 3. Doolittle, R. F., Fibrinogen and Fibrin pp. 110-111, 116-161.
Putnam, F. W., Ed. The Plasma Proteins, 2nd Ed., Section 4. Clamp, J. R. Structure and Functions, pp. 163-211, esp. 164, 173 and 174, 1975.
Siedentop et al., Autologous Fibrin Tissue Adhesive, Laryngoscopy, vol. 95, pp. 1074-1076, 1985.
Spotnitz et al., Fibrin Glue from Stored Human Plasma, The American Surgeon, Aug. 1987, No. 8; 460-462.
Lozina-Lozinskii, Studies In Cryobiology, pp. 195-203.
Gestring et al, Autologous Fibrinogen for Tissue-Adhesion, etc. Vas. Surg., vol. 17 (1982), pp. 294-295.
Dresdale et al, Preparation of Fibrin Glue, Etc. Surgery, vol. 96 (1985), pp. 750-751.
Siedentrop et al, Autologous Fibrin Tissue Adhesive, Laryngoscopy, vol. 95 (1985), pp. 1074-1075.

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