Phase sensitive differential polarimetry technique and apparatus

Details Phase sensitive differential polarimetry technique and apparatus Phase sensitive differential polarimetry technique and apparatus

1988-10-21

1990-03-27

Dority, Jr., Carroll B.

Chemistry: molecular biology and microbiology

Apparatus

Bioreactor

356364, 250225, C12M 134

Patent

active

049120590

ABSTRACT:
A differential polarimeter is disclosed for detecting changes in optical rotation between a test cell and reference cell. The test cell contains a fluid sample exposed to an analyte specific enzyme; the reference cell contains a fluid sample not exposed to the enzyme. To enhance the sensitivity of the system a phase sensitive differential polarimetric technique is taught. In this technique, the phase difference between two resulting sinewave voltages is a measure of analyte concentration.

REFERENCES:
patent: 3856408 (1974-12-01), Hill et al.

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