Pharmacologically active substituted benzamides

Details Pharmacologically active substituted benzamides Pharmacologically active substituted benzamides

1989-08-22

1991-04-30

Robinson, Douglas W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564150, 564156, 564162, 560251, C07C23300, C07C24100, C07C32100

Patent

active

050119923

ABSTRACT:
Novel substituted benzamides of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and A are as defined herein are useful in the treatment of emesis, and particularly chemotherapy-induced emesis in cancer patients. Some of the compounds are also useful in disorders relating to impaired gastric motility.

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