Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1999-03-30
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483171, 5483181, 5483215, A61K 31415, C07D23378, C07D23386, C07D23396
Patent
active
058890378
ABSTRACT:
##STR1## Compounds of formula (I), wherein R.sub.1 is an electronegative substituent such as nitro, halogeno or cyano group and R.sub.2 is a group selected from (Ia) and (Ib), wherein R is hydrogen, or an alkyl, cycloalkyl, aralkyl or aryl group, wherein X.sub.1, X.sub.2, Y and Z are independently oxygen, sulfur of NR, wherein R may be as defined above and pharmaceutically acceptable esters and salts thereof are useful in the prevention or treatment of tissue damage induced by lipid peroxidation.
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Backstrom Reijo
Honkanen Erkki
Korkolainen Tapio
Linden Inge-Britt
Nissinen Erkki
Kessinger Ann M.
Orion-yhtyma Oy
Shah Mukund J.
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