Pharmacologically active catechol derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514391, 544299, 544306, 548146, 5483171, 5483215, 5483315, 5483331, A61K 314166, C07D23378, C07D23386, C07D23396

Patent

active

061213039

ABSTRACT:
A compound of formula I ##STR1## wherein R.sub.1 is nitro, halogeno or cyano group and R.sub.2 is a group selected from ##STR2## wherein Y and Z are independently oxygen, sulfur or NR, wherein R is hydrogen, straight or branched C.sub.1-8 alkyl, C.sub.5-7 cycloalkyl, phenylC.sub.1-8 alkyl or phenyl group and X.sub.1 and X.sub.2 are NR, where R is hydrogen, straight or branched C.sub.1-8 alkyl, C.sub.5-7 cycloalkyl, phenylC.sub.1-8 alkyl or phenyl group, or a pharmaceutically acceptable salt or ester thereof. Pharmaceutical compositions are also disclosed.

REFERENCES:
patent: 4264617 (1981-04-01), Bharucha et al.
patent: 4650876 (1987-03-01), Mirviss
patent: 5208250 (1993-05-01), Cetenko et al.

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