Pharmacological association between N-acetylcysteine and levulos

Details Pharmacological association between N-acetylcysteine and levulos Pharmacological association between N-acetylcysteine and levulos

1998-01-14

1999-10-05

Lee, Howard C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514562, A61K 3170, A61K 31195

Patent

active

059624213

ABSTRACT:
A method for prevention of cell death, and method comprising simultaneously topically applying N-acetylcysteine and levulose as an application in an amount effective to result in a synergistic action protecting cells, and preventing cell damage caused by various agents. A method of preparing pharmaceutical compounds that protect cells against damage induced by a member selected from the group consisting of hypoxia/anoxia, oxidative stress, xenobiotic agents, ionizing radiations, and conditions causing toxic stress, which involves forming a combination comprising N-acetylcysteine and levulose. A pharmaceutical preparation including a combination of N-acetylcysteine and levulose.

REFERENCES:
patent: 4970236 (1990-11-01), Ziggiotti et al.
patent: 5292538 (1994-03-01), Paul et al.
Kaneto et al., Biochemical Journal, vol. 320 (Pt. 3) : 855-863, (Dec. 15, 1996).

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