Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1973-03-20
1979-10-23
Hines, Robert V.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
544230, 544398, 544403, 2603268, 2605011, 260558R, 260566A, 260566AR, 260578, 260590FA, 562492, 424250, 424267, 424274, 424316, 424330, 546 15, 546205, 546206, C07C 8728
Patent
active
041720938
ABSTRACT:
The present invention relates to new pharmacodynamically active compounds of the general structure ##STR1## as well as the corresponding amine oxides, quarternary ammonium compounds and salts with physiologically acceptable acids. In formula I R.sup.1 signifies hydrogen, halogen or alkoxy radicals having 1-3 carbon atoms, R.sup.2 and R.sup.3 signify alkyl radicals having 1-3 carbon atoms, which togetner with the carbon atom, to which they are connected, may form a ring, A either signifies a possibly lower alkyl substituted ethylene, trimethylene or tetramethylene group, in which case D is a group ##STR2## wherein R.sup.4 and R.sup.5 individually signify hydrogen or alkyl groups having 1-4 carbon atoms, or together with the nitrogen atom form a heterocyclic ring, which in addition to said nitrogen atom may contain an oxygen atom or possibly lower alkylated amino group, or A and B taken together signify a piperidino- or N-lower alkylpiperidino group, which is connected to an indene residue in 4-position, and the broken lines signify a double bond in either endo- or exo position.
REFERENCES:
patent: 3308157 (1967-03-01), Robertson et al.
patent: 3419560 (1968-12-01), Beronstein et al.
patent: 3505404 (1970-04-01), Petersen et al.
patent: 3657440 (1972-04-01), Werner
Goransson-Dahlander Barbro K.
Jonsson Nils A.
Merenyi Ferenc
AB Kabi
Hines Robert V.
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