Pharmaceutically stable oxaliplatinum preparation for...

Details Pharmaceutically stable oxaliplatinum preparation for... Pharmaceutically stable oxaliplatinum preparation for...

2006-07-04

2006-07-04

Sheikh, Humera N. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S400000, C424S423000

Reexamination Certificate

active

07070796

ABSTRACT:
The invention concerns a pharmaceutically stable oxaliplatinum preparation for parenteral administration, the oxaliplatinum being in a precipitate-free, colorless and clear solution after being preserved for a pharmaceutical acceptable duration. In said preparation, the oxaliplatinum is contained in a solution in a solvent at a concentration of at least 7 mg/ml and the solvent comprises a sufficient amount of at least a hydroxylated derivative selected among 1,2-propane-diol, glycerol, maltitol, saccharose and inositol. The invention also concerns a method for preparing said solution.

REFERENCES:
patent: 4439181 (1984-03-01), Blackshear et al.
patent: 5716988 (1998-02-01), Ibrahim et al.
patent: 5897871 (1999-04-01), Schlipalius
patent: WO 94/12193 (1994-06-01), None
patent: WO 96/04904 (1996-02-01), None
patent: WO 98/39009 (1998-09-01), None
patent: WO 99/43355 (1999-09-01), None

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