Pharmaceutically protected percutaneous devices

Details Pharmaceutically protected percutaneous devices Pharmaceutically protected percutaneous devices

1988-11-23

1990-09-25

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604280, 604 93, A61M 500

Patent

active

049590545

ABSTRACT:
A percutaneous implant device includes a structure for storing a bioreactive agent such as an antimicrobic agent, an anti-inflammatory drug, a growth hormone, and an antifungal drug. The structure can take the form of a container or a solid solution. The percutaneous device has a conduit, and the structure containing the bioreactive agent is disposed under the skin and around the conduit in the vicinity where the conduit passes through the skin of the living host. The structure containing the bioreactive agent is refillable via either a wall which is penetrable and reseals after penetration, or an access opening which can be opened or closed and is accessible from outside the living host. The container can include a wall having a diffusion coefficient which increases the rate of diffusion with increasing local temperature.

REFERENCES:
patent: 3447161 (1969-06-01), Weikel
patent: 4578063 (1986-03-01), Inman et al.
patent: 4676782 (1987-06-01), Yamamoto et al.
patent: 4810246 (1989-03-01), Frisch et al.
W. L. Gore & Associates, Inc., Peritoneal Catheter.
Study Results of the Premarket VITACUFF Infection Control Device, publication date unknown.
Gross-Siestrup et al, "Design Criteria for Percutaneous Devices," Journal of Biomedical Materials Research, vol. 18, pp. 357-382 (1982).

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