Pharmaceutically efficacious pteridine derivatives

Details Pharmaceutically efficacious pteridine derivatives Pharmaceutically efficacious pteridine derivatives

1988-10-05

1989-10-17

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544260, A61K 3150

Patent

active

048747637

ABSTRACT:
A pharmaceutically efficacious pteridine compound of formula: ##STR1## wherein R.sub.1 is hydrogen, halogen, trifluoromethyl, nitro, a --(A).sub.n --OR.sub.3 group, wherein R.sub.3 is hydrogen or a C.sub.1-6 alkyl group, a --(A).sub.n --NR.sub.4 R.sub.5 group, wherein R.sub.4 and R.sub.5 independently of each other are hydrogen or a C.sub.1-6 alkyl group or R.sub.4 and R.sub.5 together with the nitrogen atom form a 5- or 6-membered ring that is substituted with a C.sub.1-4 alkyl group and wherein A is a linking group having 1 to 6 linking carbon atoms, one of which can be replaced by oxygen and wherein n is zero or one, and wherein R.sub.2 is hydrogen or, independently of R.sub.1, has the same meaning as R.sub.1, with the proviso that R.sub.1 and R.sub.2 are not simultaneously hydrogen, and the physiologically acceptable acid addition salts thereof.

REFERENCES:
patent: 4621085 (1986-11-01), Borchard et al.

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