Pharmaceutically active compounds and methods of use thereof

Details Pharmaceutically active compounds and methods of use thereof Pharmaceutically active compounds and methods of use thereof

2006-10-10

2006-10-10

Balasubramanian, Venkataraman (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S275000, C544S279000, C544S283000, C544S323000

Reexamination Certificate

active

07119095

ABSTRACT:
The present invention relates to dihydrofolate reductase inhibitors having an aromatic group and a heteroaromatic group linked by a methylene group; and methods of treatment and pharmaceutical compositions that utilize or comprise one or more of such dihydrofolate reductase inhibitors.

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Snyder et al., J. Med. Liban 48(4): 208-214, 2000.
Kuyper et al. J. Med. Chem, 28: 303-311, 1985.

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