Pharmaceutically active bicyclic-heterocyclic amines

Details Pharmaceutically active bicyclic-heterocyclic amines Pharmaceutically active bicyclic-heterocyclic amines

1994-10-03

1996-03-26

McKane, Joseph K.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen in the nitrogen containing substituent

544 61, 544 62, 544127, 544139, 544143, 544144, 544244, 544280, 544336, 544362, 544370, 544373, 546 23, 546113, 546118, 548113, 5483044, 5483047, 5483061, 5483064, 5483067, 5483071, 5483094, 548414, 548415, 548466, 548484, 548485, 548486, 548490, 548491, C07D26504

Patent

active

055021875

ABSTRACT:
The pharmaceutically active bicyclic heterocyclic amines (XXX) ##STR1## where W.sub.1 is --N.dbd. or --CH.dbd.; W.sub.3 is --N.dbd. or --CH.dbd.; W.sub.5 is --N.dbd. or --CR.sub.5 -- with the proviso that W.sub.5 is --CR.sub.5 -- when both W.sub.1 and W.sub.3 are --N.dbd. which are useful as pharmaceuticals in treating mild and/or moderate to severe head injury, subarachnoid hemorrhage and subsequent ischemic stroke, asthma and reduction of mucous formation/secretion in the lung and other diseases and injuries.

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CA 44, 2041b, 9-Aminoacridine and methyl derivative, Falk, 1950.
Eger et al., The J. Heterocyclic. Chem., 24, 425 (1987).
Journal of Heterocyclic Chemistry, B, Venugopalan, et al., vol. 25, Provo US, pp. 1633-1639 (1988).

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