Pharmaceutical vehicles for exhancing penetration and retention

Details Pharmaceutical vehicles for exhancing penetration and retention Pharmaceutical vehicles for exhancing penetration and retention

1985-05-03

1990-01-23

Maple, John S.

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Heavy metal or compound thereof

514169, 514494, 514733, 514734, 514736, 514946, 514947, A61K 3332, A61K 31315, A61K 3156, A61K 3105

Patent

active

048957275

ABSTRACT:
This invention is a method of inducing a reservoir effect in skin and mucous membranes so as to enhance penetration and retention and reduce transdermal flux of topically applied therapeutic and cosmetic pharmacologically active agents. The invention also relates to topical treatment methods involving such reservior effect enhancers, and to pharmaceutical compositions containing them.

REFERENCES:
patent: 2087162 (1937-07-01), Moore
patent: 4261982 (1981-04-01), Luedders et al.
patent: 4349536 (1982-09-01), Hausler
patent: 4440777 (1984-04-01), Zupan
patent: 4469684 (1984-09-01), Huggins et al.
Smart, C. R. MD., et al., "Clinical Experience with Nordihydroguaiaretic Acid", J. Rocky Mountain Medical, Nov. 1970, pp. 39-43.

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