Pharmaceutical use of pyridine compounds

Details Pharmaceutical use of pyridine compounds Pharmaceutical use of pyridine compounds

1995-06-02

1997-04-01

Ramsuer, Robert W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514253, 514307, 514318, 514338, 514310, 5142338, 5142282, A61K 3144, A61K 31535

Patent

active

056165811

ABSTRACT:
A pyridine compound of the formula ##STR1## wherein R.sup.1 is a hydrogen, a halogen, an alkyl, an alkoxy or the like, R.sup.2 and R.sup.3 are each a hydrogen, a halogen or an alkyl, --P.dbd.Q-- is --CH.dbd.CH--, --N.dbd.CH-- or --CH.dbd.N--, A is an oxygen atom, a sulfur atom or N(R.sup.4) wherein R.sup.4 is hydrogen, alkyl or the like, n is 0, 1 or 2, B is S(O)p wherein p is 0, 1 or 2, D is a single bond, an alkylene or the like and E is an alkoxyalkyl or --N(R.sup.6)(R.sup.7), and a pharmaceutically acceptable salt thereof have antibacterial activity against Helicobacter pylori, antiulcer activity, gastrointestinal cytoprotective activity, ulcer recurrence, relapse-preventive activity and gastric acid secretion-suppressive activity and are useful as pharmaceutical preparations.

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Derwent Publications, Ltd., Abstract No. B0186 (1994) (abstract of JP 06100449-A).
Derwent Publications, Ltd., Abstract No. B0200 (1991) (abstract of JO 3038523A).
Derwent Publications, Ltd., Abstract No. B0205 (1991) (abstract of JO 3048680A).
Derwent Publications, Ltd., Abstract No. B0143 (1991) (abstract of JO 3052887A).
Derwent Publications, Ltd., Abstract No. B0125 (1991) (abstract of JO 3052812A).

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