Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid a

Details Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid a Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid a

1995-06-07

1997-09-30

Dentz, Bernard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514455, A61K 31445, A61K 31455

Patent

active

056726147

ABSTRACT:
The invention relates to pyridine-2,4- and -2,5-dicarboxylic acid derivatives of the formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X have the meanings given, a process for the preparation of these compounds and their use, in particular in medicaments for influencing the metabolism of collagen and collagen-like substances or the biosynthesis of Cl.sub.q.

REFERENCES:
patent: 2654759 (1953-10-01), Suter et al.
patent: 2852519 (1958-09-01), Kruse
patent: 3781286 (1973-12-01), Minisci et al.
patent: 4067975 (1978-01-01), Yu et al.
patent: 4775763 (1988-10-01), Dalton et al.
patent: 4785111 (1988-11-01), Toda
patent: 5037839 (1991-08-01), Bickel et al.
patent: 5153208 (1992-10-01), Bickel et al.
McMillan et al., J.A.C.S., vol. 78, pp. 4077-4081(1956).
Atwell et al., J. Med. Chem., vol. 10, pp. 706-713 (1967).
Wada et al., Japan Kokai 74-00, 277 (1972); Chem. Abstracts vol. 80, 108395y (1974).
Samejima, Yakugaku Zasshi, vol. 80, pp. 1706-1712 (1960); Chem. Abstracts, vol. 55, 10439-10440e (1961).
Meyer, 19 Chemical Abstracts 2953-54 (1925).
Ustavshchikov et al., 58 Chemical Abstracts 2431e (1963).
Nesterova et al., 87 Chemical Abstracts 90773c (1977).
Organikum, Organisch Chemisches Grundpraktikum, VEB Deutscher Verlag der Wissenschaften, pp. 255-256 (15th ed. 1976).
A. Hubbuch, Schutzgruppen in der Peptidsyntheses (Teil 1): Schutzgruppentaktik, Amino-und Carboxyl-Schutzgruppen, Kontakte, Mar. 1979, pp. 15 & 19, et seq.
Houben-Weyl, Methoden der Organischen Chemie (Methods of Organic Chemistry), vol. E5, pp. 496-504, 4th Ed. 1985.
J. Org. Chem., vol. 39, No. 8 (1974), p. 1158.
Elke Langhals et al., "Eine einfache neue Synthese der Fusarinsaure und anderer 5-Alkyl-2-pyridincarbonsauren," No. 5 Liebigs Ann. Chem., pp. 930-949 (1982).
Muller et al., FEBS Letters, vol. 90, 1978, pp. 218.
K. Majamaa et al., Eur. J. Biochem, vol. 138, 1984, pp. 239-245.
V. Gunzler et al., Collagen and Rel. Research, vol. 3, pp. 71, (1983).
C. Rouiller, The Liver, vol. 2, pp. 335-476, New York, Academic Press, (1964).
Pharm. Acta Helv., vol. 44, pp. 637 (1963).
W. Muller et al., Immunbiology, vol. 155, p. 47 (1978).
Houben-Weyl, Methoden der Organischen Chemie, vol. XV/2, pp. 169-183 (1974).
Organikum, Organisch Chemisches Grundpraktikum, 822 (15th ed. 1976).
Houben-Weyl, Methoden der Organischem Chemie, vol. XV/2, pp. 103-111 (1974).
Organikum, Organisch Chemisches Grundpraktikum, 595 (15th ed. 1976).
Houben-Weyl, vol. XV/1C, pp. 381-382, (1980).
Organikum, Organisch Chemisches Grundpraktikum, 527 (15th ed. 1976).
Reid et al., Liebig's Annalen, vol. 666, pp. 148-155 (1963).
Queguiner et al., C.R. Acad. Sc. Paris, vol. 258, 5903-6 (1964), Groupe 8.
Peterson et al., J. Org. Chem. 25, pp. 565-569 (1960), Chem. Abstract 19674h, vol. 54 (1960).
Prostakov et al., Khim. Geterotsihl. Soedin., Akad. Nauk. Lavt. SSR, pp. 531-536 (1965); Chem. Abstracts 3464f, vol. 64 (1966).
Elke Langhals et al., "Eine einfache neue Synthese der Fusarinsaure und anderer 5-alkyl-2-pyridincarbonsauren," No. 5 Liebigs Ann. Chem., pp. 930-949 (1982).

Affiliated with

Also associated with

Rating

Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid a does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pharmaceutical use of pyridine-2,4- and -2,5-dicarboxylic acid a will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2256843