Pharmaceutical use for cinnamamide derivatives

Details Pharmaceutical use for cinnamamide derivatives Pharmaceutical use for cinnamamide derivatives

1990-01-29

1992-05-26

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514613, 514615, 514620, A01N 3718

Patent

active

051168774

ABSTRACT:
A cinnamamide derivative represented by the formula ##STR1## wherein X is a halogen atom is useful as a muscle relaxant.

REFERENCES:
patent: 3780102 (1973-12-01), Bayssat et al.
patent: 4190647 (1980-02-01), Grivsky
patent: 4309444 (1982-01-01), Grivsky
Dialog Information Services, file 5: Biosis 66-90, accession No. 0018138375 "Cinflumide a chemically novel centrally acting skeletal muscle relaxant".
J. Med. Chem., vol. 9, No. 5, May 1966, pp. 675-681; E. Van Heyningen et al. "N-monoalkyl-beta-alkylcinnamamides as sedatives".
Arzneim-Forsch./Drugs Red., vol. 27, No. 8, Aug. 1977, pp. 1612-1615 "Elektro-myographische Untersuchungen zur Wirkung des Zimtsaurederivats . . . ".
E. Van Heymingen, et al., J. Med. Chem., vol. 9 (No. 5) pp. 675-681 (May 1966).

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