Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined...
Patent
1989-06-15
1991-05-07
Robinson, Douglas W.
Drug, bio-affecting and body treating compositions
Extract, body fluid, or cellular material of undetermined...
424574, A61K 3500
Patent
active
050135589
ABSTRACT:
The present invention relates to pharmaceutical compositions for cerebral and neuronal diseases containing physiologically active substances extracted from infected tissues. The physiologically active substances of the present invention have NGF-like nerve growth stimulating effect. Therefore, the substances of the invention are useful as drugs for various cerebral and neuronal diseases such as dementia, post-herpetic neuralgia, brain edema and spino-cerebellar degeneration.
REFERENCES:
Sprumont in Experimentia 43:671 (1987).
Morita et al., "Differential Action of Nerve Growth Factor, Cyclic Amp & Neurotropin on PC12h Cells" Cell Structure & Function 13, 227-234 (1988).
Dan et al., "The Effect of Nerve Blocks & Combination of Drugs on Post Herpetic Neuralgia" JPN J Anesthesiol 30(3) 1981, pp. 285-290.
Nippon Zoki Pharmaceutical Co. Ltd.
Robinson Douglas W.
Witz Jean
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