Pharmaceutical tablet system that floats on gastric fluid...

Details Pharmaceutical tablet system that floats on gastric fluid... Pharmaceutical tablet system that floats on gastric fluid...

2002-03-18

2010-11-23

Sheikh, Humera N (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

C424S465000, C424S468000, C424S472000, C424S474000, C424S475000

Reexamination Certificate

active

07838028

ABSTRACT:
A tablet system for prolonged floating in or on gastric fluid for releasing therein pharmaceutically active substances in an alternate succession of substance release and no-release periods is made up of a multilayered core placed in a cup-shaped envelope. The core is made up of release layers and no-release layers devoid of pharmaceutically active substance, superposed in alternate succession. The cup-shaped envelope covers bottom and side surfaces of the core while leaving exposed an upper surface of the core. The cup-shaped envelope provides for buoyancy by being formed of a compression-sintered mixture comprising hydrophobic material and inert powdered filler. The hydrophobic material is composed of fatty and/or waxy material capable of being sintered by compression and whose bulk density is lower than gastric fluid density. The powdered filler has a loose powder density that is lower than gastric fluid density.

REFERENCES:
patent: 3976764 (1976-08-01), Watanabe et al.
patent: 4101650 (1978-07-01), Umezawa
patent: 4126672 (1978-11-01), Sheth et al.
patent: 4140755 (1979-02-01), Sheth et al.
patent: 4167558 (1979-09-01), Sheth et al.
patent: 4193985 (1980-03-01), Bechgaard et al.
patent: 4434153 (1984-02-01), Urquhart et al.
patent: 4702918 (1987-10-01), Ushimaru et al.
patent: 4735804 (1988-04-01), Caldwell et al.
patent: 4758436 (1988-07-01), Caldwell et al.
patent: 4767627 (1988-08-01), Caldwell et al.
patent: 4814178 (1989-03-01), Bolton et al.
patent: 4814179 (1989-03-01), Bolton et al.
patent: 4844905 (1989-07-01), Ichikawa et al.
patent: 4996058 (1991-02-01), Sinnreich
patent: 5002772 (1991-03-01), Curatolo et al.
patent: 5169639 (1992-12-01), Baichwal et al.
patent: 5198229 (1993-03-01), Wong et al.
patent: 5213794 (1993-05-01), Fritsch et al.
patent: 5213808 (1993-05-01), Bar-Shalom et al.
patent: 5232704 (1993-08-01), Franz et al.
patent: 5288506 (1994-02-01), Spickett et al.
patent: 5360793 (1994-11-01), Brooks
patent: 5374430 (1994-12-01), Newton et al.
patent: 5571533 (1996-11-01), Santus et al.
patent: 5626876 (1997-05-01), Muller et al.
patent: 5651985 (1997-07-01), Penners et al.
patent: 6342249 (2002-01-01), Wong et al.
patent: 0 202 159 (1986-11-01), None
patent: 0 526 863 (1993-02-01), None
patent: 0 631 775 (1995-01-01), None
patent: 0 669 129 (1995-08-01), None
patent: 0 788 790 (1997-08-01), None
patent: 0788790 (1997-08-01), None
patent: 0788790 (1997-08-01), None
patent: 1 074 249 (2001-02-01), None
patent: 1 546 448 (1979-05-01), None
patent: 1016715 (1989-01-01), None
patent: 310615 (1991-04-01), None
patent: 5500668 (1993-02-01), None
patent: 06 024959 (1994-02-01), None
patent: 6024959 (1994-02-01), None
patent: 91/04015 (1991-04-01), None
patent: 93/24124 (1993-12-01), None
patent: 96/29054 (1996-09-01), None
patent: 97/47285 (1997-12-01), None
patent: 98/31341 (1998-07-01), None
patent: 98/42311 (1998-10-01), None
patent: 98/47506 (1998-10-01), None
patent: 98/52547 (1998-11-01), None

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