Pharmaceutical tablet, pharmaceutical granulate and process for

Details Pharmaceutical tablet, pharmaceutical granulate and process for Pharmaceutical tablet, pharmaceutical granulate and process for

1988-03-02

1990-08-21

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424499, 424501, 424465, A61K 920, A61K 916

Patent

active

049504843

ABSTRACT:
A pharmaceutical tablet containing an amphoteric beta-lactam antibiotic, microcrystalline or micro fine cellulose or a mixture of both and a second disintegrant, being low-substituted hydroxypropylcellulose, which fully disintegrates in water within 60 seconds. When swallowed it shows a bioavailability as good as a pharmacy prepared suspension of the antibiotic. The tablet is compressed from a mixture containing a new granulate which is prepared from the antibiotic substance, microcrystalline and/or micro fine cellulose and water only. Such tablets can also be prepared by using other known tablet disintegrants as the second disintegrant.

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