Pharmaceutical tablet composition

Details Pharmaceutical tablet composition Pharmaceutical tablet composition

1979-10-01

1981-03-03

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 19, 424 21, 424 22, 424 80, 424182, 424357, 424361, A61K 920, A61K 31705, A61K 4700

Patent

active

042540992

ABSTRACT:
A pharmaceutical tablet composition for oral administration is disclosed which provides for accelerated release <> of a finely divided active ingredient contained therein which is only slightly soluble < in the gastrointestinal tract of a warm-blooded animal >. The tablet composition is characterized as containing a micro-dispersed, amorphous, porous silica having a primary particle size of between about 1 and 15 .mu.m, a BET surface of between about 350 and 450 m.sup.2/ g, and a pore volume of between about 1.4 and 1.7 ml/g. A method of producing the tablet composition is also disclosed.

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