Pharmaceutical sustained-release compositions

Details Pharmaceutical sustained-release compositions Pharmaceutical sustained-release compositions

1982-07-30

1985-02-12

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Identification or warning feature

Taste or smell or chemical irritation to the eye, nose, or...

424 22, 424 32, 424 33, 424 81, A61K 926, A61K 932

Patent

active

044990669

ABSTRACT:
New pharmaceutical sustained-release compositions, formulated as tablets, are prepared by mixing the active ingredient with excipient already granulated and coated with polymers and/or copolymers or a polymers- and/or copolymers-mixture substantially insoluble in water. Such pharmaceutical preparations enable one to enhance or to decrease very easily and precisely the sustained-release effect by regulating the granulometry of the excipient, the excipient/active ingredient ratio, the hardness, and the percentage of the polymers and/or copolymers or of the polymers- and/or copolymers-mixture.

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