Pharmaceutical salt of...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S319000, C546S205000

Reexamination Certificate

active

07439365

ABSTRACT:
The present invention relates to the oxalate salt of 1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl]methyl piperidine, commonly known as Donepezil, and its method of preparation.

REFERENCES:
patent: 6245911 (2001-06-01), Imai
Rouhi et al. “The right stuff” Chem. eng. New, Feb. 2003, p. 32-35.
Berge et al. “Pharmaceutical salts” J. Phar. Sci. v.66, p. 1-19 (1977).
Conyers et al. “The relation of clinical catastrophes . . . ” CA 113:228637 (1990).
Lenin et al. “Attenuation of oxalate . . . ” CA 137:103659 (2002).
Jain et al. “Polynmorphism in parmacy” INdan Drugs, 23(6) p. 315-329 (1986).
Otsuka et al. “Effect of polymorphic forms of . . . ” Chem. Pharm. Bull 47(6) 852-856 (1999).
Taday et al. “Using terahertz pulse spectroscopy . . . ” J. Pharm Sci. 92(4) 831-838 (2003).
Exhibit A and B.

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