Pharmaceutical product, in medical bandage form

Details Pharmaceutical product, in medical bandage form Pharmaceutical product, in medical bandage form

1986-07-17

1988-09-06

Kight, John

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424447, A61K 970

Patent

active

047690283

ABSTRACT:
The present invention is related to a pharmaceutical product preferably in medical bandage form, for the controlled release of a therapeutically active agent or several such agents to the skin. The pharmaceutical product of the invention consists of an impermeable backing layer, a particularly composed supersaturated reservoir layer for the therapeutically active agent connected therewith and comprising a polymer matrix wherein the therapeutically active agent is soluble and which is permeable to the active agent, an adhesive layer connected with the reservoir layer and permeable to the active agent, and a cover layer covering and adhering to said adhesive layer and removable therefrom for the use of the pharmaceutical product as transdermal therapeutic system, said reservoir layer for the therapeutically active agent consisting of a multitude of layers wherein the concentration of the therapeutically active agent increases from layer to layer with increasing distance from the adhesive layer, and process for producing such a pharmaceutical product.

REFERENCES:
patent: 3598122 (1971-08-01), Zoffaroni
patent: 4286592 (1981-09-01), Chandrasekaran
patent: 4289795 (1981-09-01), Bogentoft et al.
patent: 4297995 (1981-11-01), Golub
patent: 4314557 (1982-02-01), Chandrasekaran
patent: 4341759 (1982-07-01), Bogentoft et al.

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