Pharmaceutical product for the sustained release of ibuprofen

Details Pharmaceutical product for the sustained release of ibuprofen Pharmaceutical product for the sustained release of ibuprofen

1986-12-19

1989-09-19

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424465, 424481, 424482, 42721331, 514963, A61K 936, A61K 958, B01J 1302

Patent

active

048679879

ABSTRACT:
The product consists of tablets which contain at least 600 mg of ibuprofen and a binder, or a mixture of binders, based on cellulose and cellulose derivatives in the form of microspheres which are coated with an acrylic resin of defined nature and are compressed together with a disintegrant; the tablets are preferably also coated with a lacquer layer. As a consequence of the high content of active compound and its delayed release in the body, the therapeutic treatment with ibuprofen can be reduced to a minimum number of intakes and dose units per day.

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patent: 4092350 (1978-05-01), Miura et al.
patent: 4447454 (1984-05-01), Lednicer
patent: 4522826 (1985-06-01), Sunshine et al.
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patent: 4666705 (1987-05-01), DeCrosta et al.
patent: 4684516 (1987-08-01), Bhutani
Summary of Pre-Examination Search Report.
Computer Printouts from Am. Chemical Society and Derwent Publications.
Datasheets in respect of Chemical Abstracts, WPI and WPIL.
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Merck Index pp. 601 and 1092 (1983).

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