Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1998-03-30
2000-07-04
Moezie, F. T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
424426, 424430, 424434, 1281131, 1281141, 1281151, 128800, 128834, 128839, 530828, A61K 3808, A61K 3809
Patent
active
060839163
ABSTRACT:
A drug comprising either a peptide having the LH-RH action or an LH-RH antagonist is carried on an intrauterine contraceptive device (IUD) so as to be able to provide controlled release. Once the IUD is put in the uterus, the carried drug is gradually released over such a prolonged period of treatment time as, for example, several months to be continuously absorbed through the uterus mucosa or the vagina mucosa. This construction makes it possible to reduce the patient's pain and such a troublesomeness as frequent drug administration and continuously administer a necessary drug over a prolonged period of time while taking a contraceptive measures.
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Masaharu Asano et al., "In Vivo Characteristics of Low Molecular Weight Copoly(L-Lactic Acid/Glycolic Acid) Formulations with Controlled Release of Luteinizing Hormone-Releasing Hormone Agonist", Journal of Controlled Release, Vol. 9, No. 2, Jul. 1989, pp. 111-122.
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Futo Tomomichi
Nonomura Muneo
Shimizu Hisayoshi
Moezie F. T.
Takeda Chemical Industries Ltd.
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