Pharmaceutical product comprising anti-secretory protein...

Drug – bio-affecting and body treating compositions – Extract – body fluid – or cellular material of undetermined... – Egg enclosed in shell or a part thereof

Reexamination Certificate

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C424S094100, C426S614000

Reexamination Certificate

active

06863903

ABSTRACT:
The invention generally relates to the use of natural anti-secretory protein (NASP) for the preparation of NASP-enriched functional food products or pharmaceutical products for the treatment and prophylaxis of disease-like conditions caused by extreme body fluid discharge. In particular, the invention relates to the use of NASP-enriched egg yolk as a source of NASP.

REFERENCES:
patent: 5464637 (1995-11-01), Horikawa et al.
patent: 6537588 (2003-03-01), Lange et al.
patent: 466331 (1990-01-01), None
patent: WO 9708202 (1997-03-01), None
patent: WO 9821978 (1998-05-01), None
Lonnroth et al., “The Antisecretory Factors: Inducile Proteins Which Modulate Secretion in the Small Intestine”, Comp. Biochem. Physiol., vol. 90A, No. 4, p. 611-617, 1988.*
Lange et al. “Antisecretory factor enhances in vivo internalization of cholera toxin and of horseradish peroxidase into rat entreocytes”, APMIS, 1994, vol. 102, No. 6, p. 465-473, abstract.*
McEwan et al., “Effect of antisecretory factor onEscherichia coliSTa enterotoxin-induced alkalinisation of pig jejunal acid microclimate”, Pflugers Arch, 1990, 417(2):174-9.*
McEwan et al., “Influence of Age on Antisecretory Factor Inhibition of Enterotozin Action in the Pig Small Intestine”, J. Vet. Med, A 38, 222-228, 1991.*
Lange et al., “Effects of the antisecretory factor in pigs”, Pflugers Arch, 1987, 409:328-332.*
Lange et al.,British Poultry Science, vol. 35, 1994, pp 615-620.
Lange et al., “Antisecretory factor enhances in vivo internalization of cholera toxin and of horseradish peroxidase into rat enterocytes,” APMIS, 102(6) pp. 465-473 (1994).

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