Pharmaceutical process and compounds prepared thereby

Details Pharmaceutical process and compounds prepared thereby Pharmaceutical process and compounds prepared thereby

2004-01-12

2008-10-21

Morris, Patricia L (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07439367

ABSTRACT:
The present invention relates to an improved process for the preparation of a sulfinyl compound of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, from a sulfide compound of formula (II), wherein in both formulae (I) and (II) R1and R3are selected from the group consisting of hydrogen, methyl or C1-4alkoxy, R2is selected from the group consisting of substituted or unsubstituted C1-4alkoxy and R4is selected from the group consisting of hydrogen or substituted or unsubstituted C1-4alkoxy.

REFERENCES:
patent: 4555518 (1985-11-01), Rainer
patent: 4758579 (1988-07-01), Kohl et al.
patent: 6107312 (2000-08-01), Kohl et al.
patent: 2142459 (1999-12-01), None
Vippagunta et al., “Crystalline Solids”, Advanced Drug Delivery Reviews 48 (2001) 3-26.
Guillory, “Generation of Polymorphs, etc.,” in Brittain ed., Polymorphism, etc., NY: Marcel Dekker, Inc., 1999, 183-226.
Vyas L et al: “Lansoprazole, An Antiulcerative Drug”: ACTA Crystalographica Section C. Crystal Structure Communications, Munksgaard, Copenhagen, DK, vol. C56, No. 12, 2000, pp. E572-E573, XP009014904.
Graul A. et al. “Esomeprazole Magnesium (-)-Omeprazole Magnesium Perprazole (Formerly) (S)- Omeprazole Magnesium H-199/18 Nexium”; Drugs of the Fugure, Barcelona, ES, vol. 24, No. 11, 1999, pp. 1178-1183, XP009026689.
Williams M P et al: “Review article: the pharmacology of rabeprazole”; Alimentary Pharmacology & Therapeutics, Blackwell Scientific Publications Ltd., Cambridge, GB, vol. 13, No. 3, 1999, pp. 3-10, XP002963613.
Garner A. et al: “Pantoprazole: A new and More Specific Proton Pump Inhibitor”; Expert Opinion on Investigational Drugs, Ashley Publication Ltd., London, GB, vol. 6, No. 7, 1997, pp. 885-893, XP009025982.

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