Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1985-12-06
1988-02-23
Brown, J. R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 19, 514869, A61K 3702
Patent
active
047270616
ABSTRACT:
Pharmaceutical preparations having diuretic activity and comprising a peptide of the formula ##STR1## wherein (a) R.sub.1 and R.sub.2 are hydrogen and R.sub.3 is --OH, or ##STR2## or Y, or wherein (b) R.sub.1 is hydrogen, R.sub.2 is CH.sub.2 OH or ##STR3## and R.sub.3 is --OH or Y, or wherein (c) R.sub.1 is --CH.sub.2 OH and R.sub.2 is hydrogen or ##STR4## and R.sub.3 is --OH or Y, or wherein (d) R.sub.1 is ##STR5## R.sub.2 is hydrogen or --CH.sub.2 OH and R.sub.3 is --OH, --NHCH.sub.2 COOH, or Y, and
REFERENCES:
patent: 3941763 (1976-03-01), Sarantakis
patent: 4366242 (1986-12-01), Neumann et al.
Pettit, Synthetic Peptides, vol. 1, Van Nostrand Reinhold Co., N.Y. 1970, pp. 145, 156.
Brecher et al., Chem. Abst., 72, 22 (1970), Abst. No. 284g.
Schmidbauer et al., Angew. Chem. 98 (1986), 1014-1015.
Ullmann's Encyclopedia of Industrial Chemistry, 5th Edn., vol. A4, pp. 519-531.
Kramer Herbert J.
Lehmann Klaus
Liddiard Colin
Brown J. R.
Moezie F. T.
Rohm GmbH
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