Pharmaceutical preparations having diuretic activity

Details Pharmaceutical preparations having diuretic activity Pharmaceutical preparations having diuretic activity

1985-12-06

1988-02-23

Brown, J. R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 19, 514869, A61K 3702

Patent

active

047270616

ABSTRACT:
Pharmaceutical preparations having diuretic activity and comprising a peptide of the formula ##STR1## wherein (a) R.sub.1 and R.sub.2 are hydrogen and R.sub.3 is --OH, or ##STR2## or Y, or wherein (b) R.sub.1 is hydrogen, R.sub.2 is CH.sub.2 OH or ##STR3## and R.sub.3 is --OH or Y, or wherein (c) R.sub.1 is --CH.sub.2 OH and R.sub.2 is hydrogen or ##STR4## and R.sub.3 is --OH or Y, or wherein (d) R.sub.1 is ##STR5## R.sub.2 is hydrogen or --CH.sub.2 OH and R.sub.3 is --OH, --NHCH.sub.2 COOH, or Y, and

REFERENCES:
patent: 3941763 (1976-03-01), Sarantakis
patent: 4366242 (1986-12-01), Neumann et al.
Pettit, Synthetic Peptides, vol. 1, Van Nostrand Reinhold Co., N.Y. 1970, pp. 145, 156.
Brecher et al., Chem. Abst., 72, 22 (1970), Abst. No. 284g.
Schmidbauer et al., Angew. Chem. 98 (1986), 1014-1015.
Ullmann's Encyclopedia of Industrial Chemistry, 5th Edn., vol. A4, pp. 519-531.

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