Pharmaceutical preparations for topical application and their us

Details Pharmaceutical preparations for topical application and their us Pharmaceutical preparations for topical application and their us

1988-12-07

1990-12-04

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514863, 514887, A61K 3116

Patent

active

049754661

ABSTRACT:
Pharmaceutical preparations for topical, i.e. dermal, application that contain as active ingredient a compound of the formula I ##STR1## especially 2-hydroxy-5-[(RS)-1-hydroxy-2-[[(RS)-1-(p-methoxyphenyl)-prop-2-yl]-amino] -ethyl]-formanilide (formoterol), or one of its pharmaceutically acceptable salts, especially its semifumarate, are proposed for the treatment of inflammatory skin diseases.

REFERENCES:
patent: 3994974 (1976-11-01), Murakami et al.
patent: 4268501 (1981-05-01), Konno et al.
patent: 4303637 (1981-12-01), Shell et al.
patent: 4380534 (1983-04-01), Fukui et al.
patent: 4685911 (1987-08-01), Konno et al.
Agents and Actions, vol. 19, p. 368 (1986).
Proceeding of the Society for Experimental Biology and Medicine, vol. 159, pp. 223-225 (1978).
British Journal of Dermatology, vol. 99, pp. 197-200 (1978).
Biochemical Society Transactions, vol. 14, pp. 388-391 (1986).
Derwent Abstract 40030w.
Arch. Int. Pharmacodyn, vol. 250, pp. 279-292 (1981).
CA 100: 61603 d (1984).
Allergy, vol. 38, pp. 547-552 (1983).

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