Pharmaceutical preparations for TNF inhibition

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514380, A61K 3142

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active

061178950

ABSTRACT:
Compounds of formula I ##STR1## are useful for treating TNF-mediated diseases.

REFERENCES:
patent: 4012495 (1977-03-01), Schmiechen et al.
patent: 4153713 (1979-05-01), Huth et al.
patent: 4186129 (1980-01-01), Huth et al.
patent: 4208406 (1980-06-01), Lapinet et al.
patent: 4824838 (1989-04-01), Wachtel et al.
patent: 5227369 (1993-07-01), Rosen et al.
patent: 5420154 (1995-05-01), Christensen, IV et al.
patent: 5541219 (1996-07-01), Fenton et al.
patent: 5672622 (1997-09-01), Hedgepeth et al.
patent: 5783591 (1998-07-01), Klose et al.
Strieter et al., Biochem. Biophys. Res. Comm., 155:1230-1236 (1988).
Taffet et al., Cell. Immunol., 120:291-300 (1989).
Spengler et al., Infec. Immun., 57:2837-2841 (1989).
Reeves et al., Biochem. J., 241:535-541 (1987).
Tracey et al., Nature, 330:662-664 (1987).
Old, Nature, 330:602-603 (1987).
Millar et al., Lancet, pp. 712-713 (1989).
Dezube et al., Lancet, pp. 662-663 (1990).
Perchellet et al., Cancer Letters, 29:127-137 (1985).
Perchellet et al., Carcinogenesis, 3(10):1149-1158 (1982).
Tonelli et al., Endocrinology, 77:625-634 (Oct. 1965).
Seely et al., Proceedings of the Society for Experimental Biology and Medicine, 159:223-225 (1978).
Jaiswal et al., Journal of Heterocyclic Chemistry, 15(3):519-521 (May 1978).
Schmiechen et al. (1990) Psychopharmacology, 102, pp. 17-20.
Strieter et al. (1988) Biochem. and Biophys. Research Comm. 155(3), pp. 1230-1236.
Taffet et al. (1989) Cell. Immunology 120, pp. 291-300.
Spengler et al. (1989) Infection and Immunity, 57(9), pp. 2837-2841.
Reeves et al. (1997) Biochem.J., 241, pp. 535-541.
Tracey et al. (1987) Nature, 330, pp. 662-664.
L.J. Old (1987) Nature, pp. 602-603.
Millar et al. The Lancet (1989) No. 8665, pp. 712-713.
DeZube et al., The Lancet (1989) No. 8690, pp. 662-663.
Molnar-Kimber (1992) Mediators of Inflammation, 1, pp. 411-417.
Schmiechen et al. (1990) Psychopharmacology, 102, pp. 17-20.
Molnar-Kimber et al. (1992) Mediators of Inflammation 1, 411-417.
Nicholson et al. (1991) Tips, vol. 12, (9 pages total).
Dent et al. (1990) Br. J. Pharm., vol. 22, p. 163.
Wyngaarden et al. (1992) XXIII Neurology, The Demyelinating Diseases, pp. 2219-2200.
Nataf et al. (1993) Acta Neurol Scand., 88: pp. 97-99.
Rott et al. (1993) Eur. J. Immunol. 23: pp. 1745-1751.
Schade et al. (1993) Eur. J. Pharm. 230: pp. 9-14.
Frohlich et al. (1988) J. Invest. Dermatolgy, 90: p. 240.
Adams et al. (1993) Principles of Neurology (5th Ed.) pp. 776-792.
Sharief et al. (1991) N.E. Jour. Med. 325(7), pp. 467-472.
Rentz et al. (1998) The J. of Immun., 141(7), pp. 2388-2393.
Benvenuto et al., J. of Neurology (1990) Supp 1 to vol. 237, pp. S83.
Kirby et al. (Aug. 30, 1980) The Lancet, pp. 453-454.
Renz et al. (1988) The Jour. of Immun., vol. 141 (7), pp. 2386-2393.
Marivet et al. (1989) J. Med. Chem., 32(7), pp. 1450-1457.

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