Pharmaceutical preparations and methods for their administration

Details Pharmaceutical preparations and methods for their administration Pharmaceutical preparations and methods for their administration

1997-11-17

1999-11-30

Mosley, Terressa

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424422, 424430, 424433, A61K 914

Patent

active

059938560

ABSTRACT:
Formulations which have been developed for topical or local delivery intrapelvically, intraperitoneally or directly on reproductive organs of interest administration to a region such as the female reproductive system, provide for increased comfort, increased bioavailability, rapid and relatively high blood levels in the regions to be treated in the substantial absence of systemic levels of drug which might cause side effects. These formulations consist of drug micro or nanoparticles, which may be formed of drug alone or in combination with an excipient or polymeric carrier. The excipient or polymer may be used to manipulate release rates and to increase adhesion to the affected region. The particulate formulation can be applied as a dried powder, a liquid suspension or dispersion, or as a topical ointment, creme, lotion, foam or suppository.

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