Pharmaceutical preparation in the treatment of tonsillitis

Details Pharmaceutical preparation in the treatment of tonsillitis Pharmaceutical preparation in the treatment of tonsillitis

1994-02-10

1995-01-03

Stone, Jacqueline

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Bacteria or actinomycetales

435885, 424 50, A61K 3574, C12N 120

Patent

active

053784596

ABSTRACT:
A pharmaceutical preparation in the prophylaxis against and/or the treatment of .beta.-streptococcal tonsillitis is described. The preparation includes at least one viable microorganism strain selected from the group consisting of Streptococcus sanguis II strains with the deposit numbers NCIB 40104, NCIB 40105 and NCIB 40106, the Streptococcus mitis strain with the deposit number NCIB 40107 and streptococci strains with essentially the same capacity to inhibit .beta.-streptococci as the deposited strains, in a pharmaceutically acceptable medium wherein the microorganisms retain their viability. Use of the preparation in the prophylaxis against and/or the treatment of .beta.-streptococcal tonsillitis is also described.

REFERENCES:
patent: 4454109 (1984-06-01), Hillman
patent: 4797278 (1989-01-01), Kawai et al.
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Bacteriological Reviews, vol., 1976 John R. Tagg et al: "Bacteriocins of Gram-Positive Bacteria", see pp. 722-756.
Grahn et al., I Zbl.Bakt.Hyg.A 256:72-79 (1983).
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Tagg et al, Bacteriological Reviews 40:722-756 (1976).
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Dajani et al., Antimicrob. Agents Chemother. 9:81-88 (1976).
Holm et al., Scand J Infect Dis, Suppl. 39:73-78 (1983).

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